The University of Alaska Fairbanks, located in Fairbanks, Alaska, USA, is the flagship campus of the University of Alaska System, and is abbreviated as Alaska or UAF. UAF is a land-grant, sea-grant, and space-grant institution, as well as participating in the sun-grant program through Oregon State University. It is also the site where the Alaska Constitution was drafted and signed in 1955 and 1956. UAF was established in 1917 as the Alaska Agricultural College and School of Mines, first opening for classes in 1922.

UAF is home to seven major research units: the Agricultural and Forestry Experiment Station; the Geophysical Institute, which operates the Poker Flat Research Range; the International Arctic Research Center; the Arctic Region Supercomputing Center; the Institute of Arctic Biology; the Institute of Marine Science; and the Institute of Northern Engineering. Located just 200 miles south of the Arctic Circle, the Fairbanks campus's unique location is situated favorably for Arctic and northern research. The campus's several lines of research are renowned worldwide, most notably in Arctic biology, Arctic engineering, geophysics, supercomputing, and aboriginal studies. The University of Alaska Museum of the North is also on the Fairbanks campus.

In addition to the Fairbanks campus, UAF encompasses seven rural and urban campuses: Bristol Bay Campus in Dillingham; Chukchi Campus in Kotzebue; Interior-Aleutians Campus, which covers both the Aleutian Islands and the Interior; Kuskokwim Campus in Bethel; Northwest Campus in Nome; and the UAF Community and Technical College in Fairbanks, UAF's community college arm. Fairbanks is also the home of the UAF Center for Distance Education, an independent learning and distance delivery program.

In fall 2010, UAF enrolled 11,034 students, of which 59 percent were female and 41 percent male; 89 percent were undergraduates and 11 percent graduate students.

On May 15, 2011 1,141 degree certificates were awarded to graduates of the various schools and colleges.