Lake Superior State University (colloquially referred to as Lake State, Lake Superior State and LSSU) is a small public university in Sault Ste. Marie, Michigan. It is Michigan's smallest public university with an enrollment around 3,000 students. Due to its proximity to the border, notably the twin city of Sault Ste. Marie, Ontario, LSSU has many Canadian students and maintains a close relationship with its international neighbor. In a sign of its unique situation, LSSU has both the Canadian and United States flags on its campus, and both Canadian and American national anthems are sung at athletic events.

LSSU is known for its academic programs such as fisheries and wildlife management, engineering, chemistry and the environmental sciences, teacher education, nursing, geology, business management, fire science and criminal justice. It offers Michigan's only accredited undergraduate degree program in environmental health. In addition, students attend for LSSU's degrees in forensic sciences, recreation management, and legal studies.

Lake Superior State University offers primarily bachelor's and associate's degrees, but also grants a master of arts in curriculum and instruction and many certificates. The university also offers joint programs with Sault College and Algoma University in Sault Ste. Marie, Ontario. LSSU also has regional centers located in northern Michigan in the cities of Gaylord, Escanaba, and Petoskey. Recently a center opened in southeast Michigan in the city of Dearborn. It is one of three Michigan public universities that function as both a university and a community college.